Bond markets are at the weakest levels of the day due to selling pressure associated with Draghi's press conference.  To be exact, the actual selling pressure occurred first in Treasuries at the time of the first alert (about an hour ago), but has finally spilled over to MBS markets.  Fannie 3.5s are down 6/32nds from some lenders' rate sheet print times.  As such, there is already some negative reprice potential for the early/aggressive crowd.